| Home – Away | Score | FT | UO | ||
|---|---|---|---|---|---|
 | Wohlen vs Winterthur 30 Sep – 20:00 EAT – Switzerland – Challenge League | 3-2 | 1 | U | |
 | Dunav Ruse vs Pirin Blagoevgrad 30 Sep – 20:00 EAT – Bulgaria – Parva Liga | 0-0 | 1 | U | |
 | Dijon vs Strasbourg 30 Sep – 21:00 EAT – France – Ligue 1 | 1-1 | 1 | U | |
| Guingamp vs Toulouse 30 Sep – 21:00 EAT – France – Ligue 1 | 1-1 | 1 | U | |
 | Mouscron vs KV Mechelen 30 Sep – 21:00 EAT – Belgium – Jupiler League | 2-2 | 1 | U | |
| Waasland-Beveren vs Antwerp 30 Sep – 21:00 EAT – Belgium – Jupiler League | 3-0 | 2 | O | |
 | Wisla vs Jagiellonia 30 Sep – 21:30 EAT – Poland – Ekstraklasa | 0-0 | X | U |