| Home – Away | Score | FT | UO | ||
|---|---|---|---|---|---|
 | Akhisar Genclik Spor vs Fenerbahce 29 Sep – 20:00 EAT – Turkey – Super Lig | 1-0 | 2 | O | |
 | Al-Shabab vs Al-Nasr 29 Sep – 20:15 EAT – Saudi Arabia – Saudi Professional League | 0-1 | 1 | O | |
 | Isloch Minsk vs Slavia Mozyr 29 Sep – 20:30 EAT – Belarus – Vysshaya Liga | 1-0 | 2 | U | |
 | Paris FC vs Nimes 29 Sep – 21:00 EAT – France – Ligue 2 | 2-1 | 2 | U | |
| Tours vs Brest 29 Sep – 21:00 EAT – France – Ligue 2 | 1-2 | 2 | U | |
 | Den Bosch vs Jong PSV 29 Sep – 21:00 EAT – Netherlands – Eerste Divisie | 5-0 | 1 | O | |
 | Schalke vs Bayer Leverkusen 29 Sep – 21:30 EAT – Germany – Bundesliga | 1-1 | 1 | O |