| C | Time | Home – Away | Score | FT | UO | |
|---|---|---|---|---|---|---|
 | 17:00 EAT | Crotone vs Empoli | 4-1 | 2 | U | |
| 17:00 EAT | Udinese vs AC Milan | 2-1 | 2 | U | |
 | 17:30 EAT | SC Freiburg vs Hertha Berlin | 2-1 | X | U | |
 | 18:00 EAT | Tubize vs Antwerp | 2-4 | 2 | U | |
 | 18:15 EAT | Espanyol vs Sevilla | 3-1 | 2 | O | |
 | 21:15 EAT | Hapoel Tel Aviv vs Hapoel Haifa | 0-0 | X | U | |
| 22:00 EAT | Mouscron vs Eupen | 3-0 | 1 | O |