| C | Time | Home – Away | Score | FT | UO | |
|---|---|---|---|---|---|---|
 | 21:00 EAT | GO Audax EC vs Kindermann SC | 1-1 | 1 | O | |
 | 21:30 EAT | Valencia vs Real Sociedad | 2-3 | X | U | |
 | 21:30 EAT | Mouscron vs Lokeren | 2-2 | 1 | O | |
 | 21:45 EAT | Middlesbrough vs Sunderland | 1-0 | 1 | O | |
 | 22:00 EAT | Metropolitanos vs Trujillanos | 1-0 | 2 | O | |
| 02:00 EAT | Dep. Anzoategui vs Dep. Tachira | 1-1 | 2 | U | |
 | 03:45 EAT | Penarol vs Palmeiras | 2-3 | 2 | U |