| C | Time | Home – Away | Score | FT | UO | |
|---|---|---|---|---|---|---|
 | 21:30 EAT | Granada CF vs Malaga | 0-2 | 2 | O | |
 | 21:30 EAT | Waregem vs Gent | 0-2 | 2 | O | |
| 21:30 EAT | KSV Roeselare vs Kortrijk | 2-3 | 2 | O | |
 | 21:45 EAT | Wolves vs Huddersfield | 0-1 | 2 | U | |
| 21:45 EAT | Walsall vs Port Vale | 0-1 | X | U | |
 | 21:45 EAT | Derry City vs Limerick | 1-1 | 1 | U | |
 | 22:00 EAT | Angers vs Guingamp | 2-0 | 1 | O |