| C | Time | Home – Away | Score | FT | UO | |
|---|---|---|---|---|---|---|
 | 20:30 EAT | CFR Cluj vs FCSB | 0-0 | 2 | O | |
 | 21:00 EAT | Lommel Utd vs Tubize | 2-1 | 1 | O | |
 | 21:00 EAT | Shelbourne vs Longford | 0-2 | 2 | O | |
 | 21:15 EAT | Arminia Bielefeld vs VfB Stuttgart | 2-3 | 2 | O | |
 | 21:30 EAT | Cesena vs Spezia | 1-0 | 1 | U | |
 | 21:45 EAT | Alaves vs Villarreal | 2-1 | 1 | U | |
 | 22:00 EAT | Nacional vs Moreirense | 0-1 | X | U |